Dopaminum

**Dopaminum**
Cognitores
ChemSpider	661
PubChem	681
DrugBank	DB00988
Natura chemica


Formula summarum	C ₈H ₁₁NO ₂
Massa molaris	153.181 g/mol

Dopaminum est compositum organicum et neurotransmissor in cerebro, quo munera systematum et remunerationis et extrapyramidalis (motuum) habet.

In nonnullis cerebri structuris dopaminum abunde invenitur, ut in substantia nigra. Inopia dopamini morbo Parkinson signum morbi proprium attribuebatur.

Receptoria neurotransmissoris quae ad dopaminum spectant, dopaminergica nominantur.

Natura chemicaRecensere

Nomen chemicum (IUPAC) est 4-(2-amino-aethyl)-benzino-1,2-diolum. Simul est catecholaminum, quare dopamini greges et catecholi et amini insunt.

Catecholum
Phenyl-aethyl-aminum

BiochemiaRecensere

Dopaminum per enzymum dopamini beta-hydroxylasis in neurotransmissorem noradrenalinum transvertitur.

PhysiologiaRecensere

In organismo dopaminum est et hormon et neurotransmissor^[1]. Synthesis imprimis ex aminoacido phenylalanini fit, quod per aminoacida ipsa tyrosini et laevodopa (L-DOPA, 3,4-dihydroxyphenylalaninum) in dopaminum convertitur. Degradatio dopamini per enzyma MAO-B et COMT fit.

Dopaminum neurotransmissorRecensere

In systematis nervosi centralis dopaminum est neurotransmissor, quae receptoria dopaminergica, ut D₂ obsidet. Liberatur dopaminum de neuronibus substantiae nigrae et areae tegmentalis ventralis.

NotaeRecensere

↑ Franco R., Reyes-Resina I., Navarro G. (Ian 2021). "Dopamine in Health and Disease: Much More Than a Neurotransmitter". Biomedicines 9 (2): 109

Nexus interni

Nexus externiRecensere

Fons nominis Latini. (Theodisce)

[1] Franco R., Reyes-Resina I., Navarro G. (Ian 2021). "Dopamine in Health and Disease: Much More Than a Neurotransmitter". Biomedicines 9 (2): 109

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