Corpusculum inclusionis

Corpuscula inclusionis sive corpuscula elementaria sunt substantiae stabiles, imprimis proteina, in cellularum nucleis cytoplasmatumve. Non raro praesentia corpusculorum inclusionis, ut sub microscopio visibilia, replicatio virorum intra bacteria vel cellulas eukaryoticas indicat. Praetera possunt esse signum morbi genetici uti formarum dementiae frontotemporalis vel morbi Parkinson.

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Exempla corpuscularum inclusionis

Corpuscula inclusionis vel in cytoplasmate vel in nucleo, sed etiam pariter in utraque structura inveniuntur.

Inclusionis corpuscula in variis cellulis organismorum eukaryotocorum inventa sunt; ut in erythrocytis, myocytibus, neuronibus.

Adhuc tria genera nota sunt: organellis progressu ineunte, praecipitatione haemoglobino abnormalo, inclusione protozois (ut in malaria).

Morbus Huntington (chorea chronica progressiva hereditaria) cum aggregatis proteini Huntingtini

↑ Munoz D. G., Wang D., Greenberg B. D. (1993). "Hirano bodies accumulate C-terminal sequences of beta-amyloid precursor protein (beta-APP) epitopes". Journal of neuropathology and experimental neurology 52 (1): 14-21
↑ Griffin P., Furukawa R., Piggott C., Maselli A., Fechheimer M. (2014). "Requirements for Hirano body formation". Eukaryotic cell 13 (5): 625-34
↑ Zatloukal K., French S. W., Stumptner C., Strnad P., Harada M., Toivola D. M., Cadrin M., Omary M. B. (2017). "From Mallory to Mallory-Denk bodies: what, how and why?". Experimental cell research 313 (10): 2033-49