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Dee Dean, incola Alpine comitatus, sella rotali surrecta lineam finalem ambulationis multiplicis sclerosis anni 2005 transgredit, duabus amicis nitiens.

Encephalomyelitis disseminata (breviter ED) sive vulgo sclerosis multiplex (ICD-10: G35) est morbus cum inflammatorius tum neurodegenerativus[1]. Inflammationes progressivae in cerebro et medulla spinali myelinum cellulas neurales cingens destringunt. Initio non raro multiplex sclerosis ut perturbationes visus sive pareses fugaces apparet. Quattuor formae decursus morbi descriptae sunt.

Signa et symptomataRecensere

Inflammationis causa cum axonorum myelinorum damnis velut reparationes sequentes tum signa et symptomata in diversis corporis regionibus oriuntur[2]. Initio non raro multiplex sclerosis perturbationes visus sive pareses fugaces apparet. Damna systematis nervosi partim reparabilia sunt, partim non.

DiagnosisRecensere

Diagnosis disseminatae encephalomyelitis criteriorum diagnosticorum ope ponatur. In criteriis McDonaldiensibus symptomata et signa collecta sunt. Signa imprimis ad mutationes diagnosticae imaginariae ope visibiles spectant.

CursusRecensere

Quattuor typi cursuum valituri sunt[3]: CIS, RRMS, PPMS, SPMS.

  • Syndroma singularis clinicalis (Anglice:Clinically Isolated Syndrome, breviter CIS)
  • Relabens remittensque Encephalomyelitis disseminata (Anglice: Relapsing-Remitting Multiple Sclerosis, breviter RRMS)
  • Primitus progressiva encephalomyelitis disseminata (Anglice: Primary Progressive Multiple Sclerosis, breviter PPMS)
  • Serius progressiva encephalomyelitis disseminata (Anglice: Secondary Progressive Multiple Sclerosis, breviter SPMS)

Nuper investigatio Bohemica per tomographiam resonantia magnetica factam elementarum morbi prodidit, ut quarta pars syndroma "CIS" affectorum iam specimina morbo pleno similia exponant[4].

Nexus interni

NotaeRecensere

  1. Haider L, Zrzavy T, Hametner S, Höftberger R, Bagnato F, Grabner G, Trattnig S, Pfeifenbring S, Brück W, Lassmann H (2016). "The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain". Brain 139: 807-15 
  2. Compston A, Coles A (2008). "Multiple sclerosis". Lancet 372: 1502-17 
  3. National Multiple Sclerosis Society: De mutata descriptione typorum apud encephalomyelitem disseminatam. (Anglice).
  4. Hynčicová E, Vyhnálek M, Kalina A, Martinkovič L, Nikolai T, Lisý J, Hort J, Meluzínová E, Laczó J (2017). Cognitive impairment and structural brain changes in patients with clinically isolated syndrome at high risk for multiple sclerosis. 264(3). pp. 482-93 .

Nexus externiRecensere

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