PTEN inducta kinasis 1

PTEN inducta kinasis 1 vel brevius PINK 1 est enzymum, quod mitochondria de damnis protegit. PINK 1 proteinum ligasem parkinum cum mitochondriis depolarisatis connectare iubet, ut illorum autophagocytosis (destructio) initietur^[1].

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PTEN inducta kinasis 1 PINK 1
Cognitores
Alia nomina	PINK-1, BRPK, PARK6
Fontes externae	OMIM: 608309
Genetica
Locus geni (homo)


Locus	1p36.12
Initium	20 633 458
Terminus	20 651 511

Mutationes geneticae momentum morbi Parkinson habere videtur^[2].

Notae

↑ Narendra D. P., Jin S. M., et al. (Ian 2010). "PINK1 is selectively stabilized on impaired mitochondria to activate Parkin". PLoS Biology 8 (1): e1000298
↑ Wu S., Lei L., et al. (Nov 2018). "Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism". Experimental neurology 309: 67-78

Nexus interni

Nexus externi

Liber: PINK 1 typus morbi Parkinson initio adulescente (Anglice)

stipula

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[1] Narendra D. P., Jin S. M., et al. (Ian 2010). "PINK1 is selectively stabilized on impaired mitochondria to activate Parkin". PLoS Biology 8 (1): e1000298

[2] Wu S., Lei L., et al. (Nov 2018). "Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism". Experimental neurology 309: 67-78

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