Kinasis

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Kinases sunt in biochemia enzyma, quae catalysis translationis phosphati ab nucletido trisphosphato (per exemplum ATP) composita chemica divita energia in substantiam aliam perificant. Munera kinasum organismi maius momentum habet.

In cellulae signis transductibus kinases iter metabolicum cum phosphatidylinositolo-4,5-bisphosphato (PIP₂) coniunctum gubernat^[1].

In medicina scientifica kinases momentum in cancerogenesi variorum cancrum habent, ut glioblastomatis multiformis^[2]. In cyclo cellulari enim cyclino dependentes kinases (CDK) cum sodalibus earum, cyclinis, cycli cursum gubernat, at gubernationis perturbationes, ut in cancris pluribus, incrementum malignum perficere possint. Putatur ut inhibitores CDK incrementum deminuere possint^[3].

Notae recensere

↑ Sun Y., Thapa N., et al. (Iun 2013). "Phosphatidylinositol 4,5-bisphosphate: targeted production and signaling". Bioessays 35 (6): 513-22
↑ Bleeker F. E., Lamba S., et al. (Sep 2014). "Mutational profiling of kinases in glioblastoma". BMC Cancer 14: 718
↑ Canavese M, Santo L., Raje N. (Mai 2012). "Cyclin dependent kinases in cancer: potential for therapeutic intervention". Cancer biology & therapy 13 (7): 451-7

Nexus interni

Hexokinasis

Nexus externi recensere

The free dictionary: Definitio kinasis

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[1] Sun Y., Thapa N., et al. (Iun 2013). "Phosphatidylinositol 4,5-bisphosphate: targeted production and signaling". Bioessays 35 (6): 513-22

[2] Bleeker F. E., Lamba S., et al. (Sep 2014). "Mutational profiling of kinases in glioblastoma". BMC Cancer 14: 718

[3] Canavese M, Santo L., Raje N. (Mai 2012). "Cyclin dependent kinases in cancer: potential for therapeutic intervention". Cancer biology & therapy 13 (7): 451-7

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