Nucleus tuberomammillaris
TMN
Nc. tuberomammillaris
Nucleus abbreviatura TMN in cerebro muris adumbratus.
TA: 14.1.08.932

Nucleus tuberomammillaris est nucleus cerebri systematis histaminergici in hypothalamo posteriore locatus.

Nucleus momentum excitationis animi[1] ac, per nervos afferentes GABAergicos[2] ex area praeoptica orientes, somnum inducendi[3] habere videtur.

Natura nuclei tuberomammillaris

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In corpore humano nucleum tuberomammillarem fontem histamini (H) unicam putatur. Axones cellularum neuronalium concurrentes densiter in corticem cerebri, hippocampum, corpus striatum, nucleum accumbentem, corpus amygdaloideum et alias hypothalami partes transferuntur. Effectus fibrae nervales in corticem currentes est corticem activans - communiter cum fibris in nucleum basalem cholinergicum currentibus, tum eo modo effectus indirecti, neurotransmissore acetylcholino (ACh), exercentes.

  1. Fujita A., Bonnavion P., Wilson M. H., Mickelsen L. E., Bloit J., de Lecea L., Jackson A. C. (Sep 2017). "Hypothalamic Tuberomammillary Nucleus Neurons: Electrophysiological Diversity and Essential Role in Arousal Stability". Journal of neurophysiology 37 (39): 9574-92 
  2. Xie J. F., Fan K., Wang C., Xie P., Hou M., Xin L., Cui G. F., Wang L. X., Shao Y. F., Hou Y. P. (Aug 2017). "Inactivation of the Tuberomammillary Nucleus by GABAA Receptor Agonist Promotes Slow Wave Sleep in Freely Moving Rats and Histamine-Treated Rats". Neurochemical research 42 (8): 2314-25 
  3. Yu X., Franks N. P., Wisden W. (Ian 2018). "Sleep and Sedative States Induced by Targeting the Histamine and Noradrenergic Systems". Frontiers in neural circuits 12: 4 

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