Nucleus septalis medialis
Cognitores
TA: A14.1.09.269

A14.1.09.446

Anatomia
Nucleus septalis medialis
Situs nuclei septalis medialis intra cerebrum muris.

Nucleus septalis medialis est unus ex nucleis septalibus et simul locus nucleorum septalium ex quo neurones in parte maiore ad corticem entorhinalem[1] et hippocampum currunt et per neurotransmissionem cholinergicam effectus suos exercent.

Nucleus septalis medialis communiter cum aliis nucleis septalibus in parte basali telencephali situs est.

Nucleus septalis medialis est pars generatorum hippocampalium EEG-undarum theta.

Nuclei septales

recensere

Nuclei septales sunt grex perykarya cellularum nervalium, in parte basali telencephali locati, infra rostrum corporis callosi et ante laminam basalem prosencephali. Perykarya greges et medialis (nucleus septalis medialis) et laterales (nucleus septalis lateralis) formant.

Iter septale-entorhinale

recensere

Nexibus ab nucleis septalibus ad corticem entorhinalem neurotransmissores duo, acetylcholinum (ACh) ac GABA, fortasse etiam glutamatum sunt[2]. Videtur, ut gubernatio genesis neurotransmissoris ACh - in hippocampo secernatus - cholini acetyltransferasi (ChAT) exprimendo fiat[3].

  1. Desikan S., Koser D. E., Neitz A., Monyer H. (Mar 2018). "Target selectivity of septal cholinergic neurons in the medial and lateral entorhinal cortex". Proceedings of the National Academy of Sciences 115 (11): E2644-52 
  2. Manns I. D., Mainville L., Jones B. E. (2001). "Evidence for glutamate, in addition to acetylcholine and GABA, neurotransmitter synthesis in basal forebrain neurons projecting to the entorhinal cortex". Jornal of neuroscience 107 (2): 249-63 
  3. Uematsu N., Matsukawa N., et al. (Dec 2009). "Overexpression of Hippocampal Cholinergic Neurostimulating Peptide in Heterozygous Transgenic Mice Increases the Amount of ChAT in the Medial Septal Nucleus". Brain Research 1305: 150-7 

Nexus interni