Mitophagia ad mitochondriorum autophagocytosem, vulnerationem sui ipsius, refert. Est iter metabolicum aequilibrio cellulae interno servans. Mitophagia una cum diversis morbis coniuncta videtur, ut morbo Alzheimerianus, diabete mellito, morbis cardiovascularibus[1].

Mitophagia: mitochondrium intra mitophagosoma

Contextus

recensere

Mitophagia genus autophagocytosis est. Intra cellulas rete mitochondrialis salubre mirabiliter pernecesse est[2].

Autophagocytosis in genere

recensere

Autophagocytosis (edere se ipsum) est pars catabolica cellularum, qua organella mala ope lysosomatum et vaculolorum destruuntur[3]. Pleraque organella cellularia autophagiae subiecta sunt. Mitophagia est cursus diversorum itinerum, quo mitochondria per mitophagosomata discutiuntur[4].

  1. Doblado L., Lueck C., et al. (Apr 2021). "Mitophagy in Human Diseases". International journal of moleclar sciences 22 (8): 3903 
  2. Pickles S., Vigié P., Youle R. J. (2018). "Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance". Current biology 28 (4): R170-85 
  3. Scott S. V., Klionsky D. J. (Aug 1998). "Delivery of proteins and organelles to the vacuole from the cytoplasm". Current opinion in cell biology 10 (4): 523-9 
  4. Zachari M., Ktistakis N. T. (Mar 2020). "Mammalian Mitophagosome Formation: A Focus on the Early Signals and Steps". Frontiers in cell and developmental biology 8: 171 
 
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