Factor crescentis insulinoideus 1

Factor crescentis insulinoideus 1 sive somatomedinum C sive abbreviaturae IGF-1 sive SM-C est proteinum septuaginta aminoacidis de origine hepatica, cuius genum nominis IGF-1 in hominibus chromosomate 12^[1] reperiuntur. Nomen insulinoideus de similitudine insulini derivatur. IGF est mediator principalis hormonatis GH (hormon crescentis) per receptorium factoris crescentis insulinoidei 1 (IGF-1R). Adhuc nonnullae functiones notae sunt, per exemplum anabolicae, sed multae obscurae vel vix apprehensae.

Similiter factor crescentis insulinoideus 2 (IGF-2) receptorium IGF-1 obsidet, IGF-2R exstat, quamquam sine functione ipsa est.

Nexus interni

Notae

↑ Höppener JWM, de Pagter-Holthuizen P, Geurts van Kessel AHM, Jansen M, Kittur SD, Antonarakis SE, Lips CJM, Sussenbach JS (1985). "The human gene encoding insulin-like growth factor I is located on chromosome 12". Hum Genetics 69 (2): 157-60

Nexus externi

Le récepteur de l'IGF1 et les hybrides IR/IGF1R (Groupe Tarik Issad) (Francogallice)

[1] Höppener JWM, de Pagter-Holthuizen P, Geurts van Kessel AHM, Jansen M, Kittur SD, Antonarakis SE, Lips CJM, Sussenbach JS (1985). "The human gene encoding insulin-like growth factor I is located on chromosome 12". Hum Genetics 69 (2): 157-60

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