Cancer vesicae

Cancer vesicae accurate carcinoma urotheliale vesicae est morbus accurate cancri species, quae vesicam urinariam attingit.

Cave: notitiae huius paginae nec praescriptiones nec consilia medica sunt.

Indicia vel symptomata possunt esse imprimis haematuria (sanguis in urina), praeterea dysuria (dolor mictione ineunte), pollakisuria (mictio frequentior), tardius dolor dorsi inferioris.

Diagnosis per urinanalysi plus alia examina medica facta est.

Fumatio ad periculum cancri vesicae addere queat.

Anatomia pathologica macroscopica

Classificatio TNM

Classificatio TNM vesicae urinariae, hic magnitudinis tumoris (T)

Classificatio TNM Tumoris magnitudinem (T), Nodorum lympathicorum affectio (N), Metastasis organorum remotorum (M) describit^[1]. "0" ulli symptomatis amissio indicat:

T₀ — nullum indicium tumoris vesicae
N₀ — nulla metastasis nodorum lymphaticorum regionalium pelvis
M₀ — nulla metastasis remota (i. e. nulla metastasis organorum remotorum)

Anatomia pathologica microscopica

Cancri vesicae cellulae in microscopio visae

Genetica pathologica

In centesimae viginti hominum mutationes geneticae inveniuntur. Ex multitudinibus genorum affectorum adhuc subtypi expressionis quinque descripti sunt: neuronalis, basalis (squamosus), luminalis, luminalis et infiltrans, luminalis et papillaris^[2].

Gena cum cancro vesicae nexa sunt: FGFR3, TP53, PIK3CA, KDM6A, ARID1A, KMT2D, HRAS, TERT, KRAS, CREBBP, RB1, TSC1^[3].

Therapia

Therapia variis modis adhibetur, ut per resectionem transurethralem, instillationes intravesicales, cystectomiam, chemotherapiam, therapiam multimodalem et organum conservantem.

Chemotherapia

In cancros vesicae tractandis Cisplatinum est substantia chemotherapeutica una cum aliis substantiis commendata^[4].

Notae

↑ Magers M. J., Lopez-Beltran A., et al. (Ian ]volume=74 2019). "Staging of bladder cancer". Histopathology (1): 112-34
↑ Robertson A. G., Kim J., et al. (Oct 2017). "Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer". Cell 171 (3): 540-56
↑ Zhang X., Zhang Y. (Sep 2015). "Bladder Cancer and Genetic Mutations". Cell biochemistry and biophysics 73 (1): 65-9
↑ Einstein D. J., Sonpavde G. (Feb 2019). "Treatment Approaches for Cisplatin-Ineligible Patients with Invasive Bladder Cancer". Current treatment options in oncology 20 (2): 12

Nexus externus

Institutum nationale cancrum de cancro vesicae (Anglice)

Vicimedia Communia plura habent quae ad Cancrum vesicae spectant (Bladder urothelial carcinoma, Urinary bladder cancer).

stipula

Haec stipula ad medicinam spectat. Amplifica, si potes!

[1] Magers M. J., Lopez-Beltran A., et al. (Ian ]volume=74 2019). "Staging of bladder cancer". Histopathology (1): 112-34

[2] Robertson A. G., Kim J., et al. (Oct 2017). "Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer". Cell 171 (3): 540-56

[3] Zhang X., Zhang Y. (Sep 2015). "Bladder Cancer and Genetic Mutations". Cell biochemistry and biophysics 73 (1): 65-9

[4] Einstein D. J., Sonpavde G. (Feb 2019). "Treatment Approaches for Cisplatin-Ineligible Patients with Invasive Bladder Cancer". Current treatment options in oncology 20 (2): 12

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