Tetrabenazinum

Tetrabenazinum est medicamentum in malis motuum hyperkineticis tractandis, ut morbo Huntington et dystoniis atque dyskinesia tardiva.

Cave: notitiae huius paginae nec praescriptiones nec consilia medica sunt.

Tetrabenazinum

Cognitores
ChemSpider	5796
PubChem	6018
DrugBank	DB04844
Natura chemica
Formula summarum	C 19H 27NO 3
Massa molaris	317.427 g/mol
Natura pharmacologica
Codex ATC	N07XX06 (WHO)
Metabolismus	iecore (hepaticus)
Excretio	renibus: 75%, faecibus: 7-16%
Ad usum therapeuticum
Applicatio	per os

Natura Tetrabenazini

Natura chemica

Tetrabenazinum est (IUPAC) (RR,SS)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo-[a]-chinolinum.

Massa molaris est 317.427 g/mol.

• 
  Piperidinum
• 
  Quinolinum

Pharmacodynamica

Tetrabenazinum receptoria dopamini obsidet inhibetque. Praeterea neurotransmissores monoaminergicos consumit.

Pharmacocinetica

Excretio est per imprimis urinas, minus per biles.

Effectus Tetrabenazini

Effectus secundarii

Exempli (!) sunt:

• Somnolentia (>30%)
• Parkinsonismus (>25%)
• Depressio (15%)
• Insomnia (>10%)

Nexus interni

• Pharmacologia