Folliculos stimulans hormon

Folliculos stimulans hormon, abbreviatura FSH, est hormon ex duabus catenis, alpha (FSHA, OMIM: 118850) et beta (FSHB, OMIM: 136530), compositum. FSH de cellula gonadotropica lobi anterioris hypophysis secernitur. Et in viribus et in muliebris hormono FSH munera propria sunt.

FSH cum receptorio eius.

Physiologia FSHRecensere

SecretioRecensere

Secretio hormontis folliculos stimulantis praecipue ab hypothalamo per decapeptidum hormon liberationis gonadotropinorum (GnRH) moderatur; secretio ipsa ab cellulas gonadotropicas, quae in lobo anteriori hypophysis sitae sunt, fit[1]. Intra hypophysi, complexus proteinorum et activini (biosynthesis FSH ↑) et inhibini (biosynthesis FSH ↓), velut follistatinum in edita moderandis agunt[2]. Activinum genum promotorem Fshb subunitatis beta lectum incitat. Subunitas alpha, ut LH, genum alphaGSU requirit.

Cyclus mensualis apud muliebresRecensere

 
Cursus FSH.

Cyclo menstruali ineunte FSH folliculos in ovariis immaturos stimulat[3].

Spermatogenesis apud virosRecensere

FSH spermatocytos in testibus virorum stimulat[4].

NotaeRecensere

  1. Sharma T. P., Nett T. M., Karsch F. J., Phillips D. J., Lee J. S., Herkimer C., Padmanabhan V. (2012). "Neuroendocrine control of FSH secretion: IV. Hypothalamic control of pituitary FSH-regulatory proteins and their relationship to changes in FSH synthesis and secretion". Biology of reproduction 86 (6): 171 doi:10.1095/biolreprod.111.098442
  2. Bilezikjian L. M., Justice N. J., Blackler A. N., Wiater E., Vale W. W. (Aug 2021). "Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin". Molecular and cellular endocrinology 359 (1-2): 43-52 doi:10.1016/j.mce.2012.01.025
  3. Messinis I. E., Messini C. I., Dafopoulos K. (2014). "Novel aspects of the endocrinology of the menstrual cycle". Reproductive biomedicine online 28 (6): 714-22 
  4. Huhtaniemi I. (2015). "A short evolutionary history of FSH-stimulated spermatogenesis". Hormones (Athens, Greece) 14 (4): 468-78 

Nexus interni

Nexus externiRecensere

  • Laboratorium et FSH. (Anglice)
  Haec stipula ad biologiam spectat. Amplifica, si potes!