FG-7142, sive ZK-31906, est medicamentum quod agonistae inverso ad allostericum benzodiazepini situm receptoris GABAA partim prodest.[1] Inter eius effectus physiologicos sunt anorexia,[2] anxiogenia, et convulsiones.[3] Acetylcholinum et noradrenalinum liberanda auget,[4] et memorias retinendas in studiis animalium emendat.[5]


  1. "Systemic administration of the benzodiazepine receptor partial inverse agonist FG-7142 disrupts corticolimbic network interactions". Synapse 61 (8): 646–63. 2007 .
  2. "FG 7142 specifically reduces meal size and the rate and regularity of sustained feeding in female rats: evidence that benzodiazepine inverse agonists reduce food palatability". Neuropsychopharmacology 32 (5): 1069–81. Maius 2007 .
  3. "Pharmacology of the β-carboline FG-7142, a partial inverse agonist at the benzodiazepine allosteric site of the GABAA receptor: neurochemical, neurophysiological, and behavioral effects". CNS Drug Reviews 13 (4): 475–501. hiems 2007 .
  4. "Effects of the vasopressin (V1b) receptor antagonist, SSR149415, and the corticotropin-releasing factor 1 receptor antagonist, SSR125543, on FG 7142-induced increase in acetylcholine and norepinephrine release in the rat". Neuroscience 141 (3): 1481–8. 2006 
  5. "GABAA receptors determine the temporal dynamics of memory retention". Learning and Memory 15 (3): 106–11. 2008 .