Duloxetinum
compositum chemicum
Duloxetinum est antidepressivum et inhibitor reabsorptionis serotonini noradrenalinique[1].
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Cave: notitiae huius paginae nec praescriptiones nec consilia medica sunt. |
| Cognitores | |
|---|---|
| ChemSpider | 54822 |
| PubChem | 60835 |
| DrugBank | DB00476 |
| Natura chemica | |
| |
| |
| Formula chemica | C 18H 19NOS |
| Massa molaris | 297.42 g/mol |
| Natura pharmacologica | |
| Codex ATC | N06AX21 (WHO) |
| Semivita biologica | 12 h |
| Metabolismus | iecore (hepaticus): CYP1A2, CYP2D6 |
| Excretio | renibus (70%), faecibus (20%) |
| Ad usum therapeuticum | |
| Applicatio | per os |
Pharmacocinetica
recensereSemivita biologica .[2] 12 h est. Duloxetinum substratum cytochromatum CYP1A2 et CYP2D6 est. Excretio est maiore in parte per renes (70%), minore per faeces (20%).
Notae
recensere- ↑ Wong D. T., Bymaster F. P. (2002). "Dual serotonin and noradrenaline uptake inhibitor class of antidepressants potential for greater efficacy or just hype?". Progress in drug research 58: 169-22
- ↑ http://goldbook.iupac.org/B00658.html
Nexus interni
Nexus externi
recensere- drugs.com cum monographia Duloxetini (Anglice)