Citrullinum

**Citrullinum**
Nomina


IUPAC	Acidum 2-amino-5-(carbamoylo-amino)- pentanoicum
Cognitores
DrugBank	DB00155
PubChem	855
Natura chemica
Formula summarum	C ₆H ₁₃N ₃O ₃
Massa molaris	175.188 g/mol
Potentia acidi (pK_a)	2.508
Potentia basis (pK_b)	11.489

Citrullinum (de citrullo lanato) in chemia est α-acidum aminicum, non in proteinis inventum.^[1] In cyclo ureae adhibetur, et in duabus e suis perturbationibus geneticis in sanguine accumulat, ambae citrullinaemia appellatae.

Praeterea functionem intestini et absorptionem in intestinum indicare possunt.

Natura chemica

Formula chemica sua est C
₆H
₁₃N
₃O
₃, et massa molaris 175.188 g/mol. Citrullinum est compositum parentale classis citrullinorum, una cum ornithino.

Nomen plenum chemicum est acidum 2-amino-5-(carbamoylo-amino)-pentanoicum. Acido valerico (pentanoico) positione 5 sua per gregrem amini grex carbamoyli nexus est, et positione 2 grex alius amini locatus est.

Acidum pentanoicum (IUPAC) sive acidum valericum; positio 1 est atomo C dextre (cum =O et -OH), 5 plane sinistre.
Grex carbamoyli per gregem NH acido valerico positione 5 eius ligatus.
Ornithinum

Usus diagnosticum

Citrullinum constanter ex intestino in sanguinem liberatur. Citrullinum functionem intestini et absorptionem in intestinum indicare possunt^[2], indicator et mali acuti et chronici. Longitudo intestini brevior ac quaedam enteropathiae (morbus coeliacus, enteropathia tropicalis, morbus Crohn, mucositis, reiectio transplantantis) valores citrullini reductae efficiunt.

Sane in muribus multitudo citrullini in sanguine rhythmo circadiano subiecta videtur^[3].

Nexus interni

Notae

↑ Pubchem de citrullino.
↑ Fragkos K. C., Forbes A. (2018). "Citrulline as a marker of intestinal function and absorption in clinical settings: A systematic review and meta-analysis". United Europea gastroenterology journal 6 (2): 181-91
↑ Park C. J., Shaughnessy M. P., Armenia S. J., Cowles R. A. (2019). "Serum Citrulline Levels Exhibit Circadian Variation and Fluctuations in Relation to Food Intake in Mice". Gastroenterology research 12 (2): 88-92

stipula

Haec stipula ad chemiam spectat. Amplifica, si potes!

[1] Pubchem de citrullino.

[2] Fragkos K. C., Forbes A. (2018). "Citrulline as a marker of intestinal function and absorption in clinical settings: A systematic review and meta-analysis". United Europea gastroenterology journal 6 (2): 181-91

[3] Park C. J., Shaughnessy M. P., Armenia S. J., Cowles R. A. (2019). "Serum Citrulline Levels Exhibit Circadian Variation and Fluctuations in Relation to Food Intake in Mice". Gastroenterology research 12 (2): 88-92

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