Degeneratio corticobasalis

Degeneratio corticobasalis (ICD-10: G31.0) (CBD abbreviata), sive degeneratio cortico-dentato-rubralis, sive degeneratio cortico-basalis-ganglionaris est morbus rarus, histopathologice definitus, neurodegenerativus et progrediens.

Cave: notitiae huius paginae nec praescriptiones nec consilia medica sunt.

Secundum locos degenerationum apparet CBD cum symptomatum ex nucleis basalibus et corticis cerebralibus orientium. Symptomata non symmetrica et syndroma membri alieni conspicua sunt.

Leniter progredentia imprimis ab annis 50-70 symptomata cum impedimentis cognitionis emergant.

Adhuc therapia causarum incognita est.

Historia

Degeneratio corticobasalis primum anno 1967, tum nomine, degenerationis cortico-dentato-nigralis cum achromasia neuronali^[1] descripta est.

Signa et symptomata

CBD cum malis motuum notabilissime non symmetricis, ut syndroma Parkinson plerumque hypokineticum et unilaterale, tremor in agendo et in attinendo, velut dystonia animadvertitur^[2].

Differentia

Differentiales diagnoses sunt, per exemplum:

Atrophia systematum multorum (MSA)
Morbus Parkinson
Paralysis supranuclearis progressiva (PSP)

Notae

↑ Rebeiz J. J., Kolodny E. H., Richardson E. P. Jr. (1967). "Corticodentatonigral degeneration with neuronal achromasia: a progressive disorder of late adult life". Transactions of the American Neurological Association 92: 23-6
↑ Lee S. E., Rabinovici G. D., Mayo M. C., Wilson S. M., Seeley W. W., DeArmond S. J., Huang E. J., Trojanowski J. Q., Growdon M. E., Jang J. Y., Sidhu M., See T. M., Karydas A. M., Gorno-Tempini M. L., Boxer A. L., Weiner M. W., Geschwind M. D., Rankin K. P., Miller B. L. (2011). "Clinicopathological correlations in corticobasal degeneration". Ann Neurol 70 (2): 327-40

Nexus interni

stipula

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[1] Rebeiz J. J., Kolodny E. H., Richardson E. P. Jr. (1967). "Corticodentatonigral degeneration with neuronal achromasia: a progressive disorder of late adult life". Transactions of the American Neurological Association 92: 23-6

[2] Lee S. E., Rabinovici G. D., Mayo M. C., Wilson S. M., Seeley W. W., DeArmond S. J., Huang E. J., Trojanowski J. Q., Growdon M. E., Jang J. Y., Sidhu M., See T. M., Karydas A. M., Gorno-Tempini M. L., Boxer A. L., Weiner M. W., Geschwind M. D., Rankin K. P., Miller B. L. (2011). "Clinicopathological correlations in corticobasal degeneration". Ann Neurol 70 (2): 327-40

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