Transportator noradrenalinae
Transportator noradrenalini Transportator norepinephrini NET SLC6A2 | |||||
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Alia nomina | NAT1, NET, NET1, SLC6A5 | ||||
Locus geni (homo) | |||||
Chromosoma | 16 (humanum) | ||||
Locus | 16q12.2 (homo) | ||||
Transportandum | noradrenalinum | ||||
Fontes externae | OMIM: 163970 |
Transportator noradrenalini sive transportator norepinephrini (abbreviatura internationalis: NET) vel cursor solubilis familiae sextae membri secundi (abbreviatura internationalis: SLC6A2) est transportator neurotransmissoris noradrenalini (norepinephrini, NE) exclusive in terminalibus neuronorum sympathicorum inventus. NET per natrio/chloro (Na+/Cl-) pendentem reabsorptionem noradrenalini extracellularis summam noradrenalini intra fissuram synapticam reducit.
Genetica
recensereGenum nomine SLC6A2 in hominibus chromosomate 16 locatum est.
Notae
recensere- ↑ Rickli A., Liakoni E., Hoener M. C., Liechti M. E. (2008). "Opioid-induced inhibition of the human 5-HT and noradrenaline transporters in vitro: link to clinical reports of serotonin syndrome". British journal of pharmacology 175 (3): 532-43