Anandamidum

**Anandamidum**
Cognitores
ChemSpider	4445241
PubChem	5281969
Natura chemica


Formula summarum	C ₂₂H ₃₇NO ₂
Massa molaris	347.53 g/mol

Anandamidum vel N-arachidonoylaethanolaminum (AEA) est neurotransmissor et acidum adipatum ab acido arachidonico, uno acidorum adipatorum omega-6 essentialium, derivatum. Pars nominis prima de Lingua Sanscrita (ananda = felicitas) Lingua Sanscrita.

Effectus anandamidi cum praesentia receptoriorum cannabinoideorum nexi sunt. Putatur quoque anandamido effectus in morbis mentis esse^[1].

Natura chemica

Compositum est anandamidum longa ex molecula acidi arachidonici per amino secundario cum aaethanolo (aeathanolamino) coniunctum. Nomen IUPAC est (5Z,8Z,11Z,14Z)-N-(2-hydroxy-aethyl)-icosa-5,8,11,14-tetraenamidum.

Biochemia

In hominibus synthesis anandamidi acidum arachidonicum requirit, ex quoN-arachidonoyl phosphatidylethanolaminum (NAPE) generatur.

Acidum arachidonicum
Aminum secundarium
Aethanolaminum
Aethanolum
(alcohol primarium)
Aminum primarium

Notae

↑ Gaetani S., Dipasquale P., Romano A., Righetti L., Cassano T., Piomelli D., Cuomo V. (2009). "The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs". International review of neurobiology 85: 57-72

Bibliographia

Mechoulam R., Fride E.: The unpaved road to the endogenous brain cannabinoid ligands, the anandamides in “Cannabinoid Receptors” (ed. R. Pertwee), Academic Press, London. Pp. 233-258 (1995).

Nexus interni

Cannabis

[1] Gaetani S., Dipasquale P., Romano A., Righetti L., Cassano T., Piomelli D., Cuomo V. (2009). "The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs". International review of neurobiology 85: 57-72

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