Testosteron
Testosteron (-onis, m.; sicut hormon)[1] vel testosteronum in maribus est naturalis et principalis hormon sexualis et steroides anabolica,[2] quae in textibus systematis reproductonis hominum crescendis magni momenti est, plerumque in testibus et prostata, ac proprietatibus sexualibus secundariis prodest, inter quas massa musculorum ossiumque, et in capillis corporis crescendis, et praeterea in psychologicis marium proprietatibus auctis, sicut incursione?, libidine, studio sociorum commovendorum, moribus amoris.[3]
Etiam ab ovariis aliquantumque glandulis adrenalibus mammalium effunditur. Primum locum obtinet hormontum virilium, nam octies aut decies maior est copia testosteronis virorum quam mulierum.
Testosteron est steroides, quo greges chemici positione 3 ketonea (=O) et positione 17 hydroxyli (-OH) sunt. Biosynthesis gradatim abs cholesterolo fit.
Testosteron per sanguinem per corpus distribuitur, ut hoc hormon in regiones remotas adferatur, deinde in cellulas transportatur, ibi ad nucleum cellulae mota, quo receptoriae androgeni sitae sunt.
Biochemia
recensereBiochemia testosteronis ad biosynthesin, interactionem in sanguine cum globulino hormonibus sexualibus liganti, velut intra cellulam ad interactionem cum nuclearibus androgenii receptoriis.
Pericula vel signa testosteronis humilis
recensereValores humiles cum variis morbis, ut morbis cardiovascularibus nexus sunt.[4].
Notae
recensere- ↑ Cfr. "Comamonas testosteronis" apud Franzetti, F.; Cernuschi, M.; Esposito, R.; Moroni, M. (Aprili 1992). "Pseudomonas infections in patients with AIDS and AIDS-related complex". Journal of Internal Medicine 231 (4): 437–443.
- ↑ Understanding the risks of performance-enhancing drugs. . Mayo Clinic.
- ↑ "Biological actions of androgens". Endocrine Reviews 8 (1): 1–28. Februarius 1987.
- ↑ Kloner R. A., Carson tertius C., Dobs A., Kopecky S., Mohler III E. R. (Februarius 2016 ). "Testosterone and Cardiovascular Disease". Journal of the American College of Cardiology 67 (5): 545-57 doi:10.1016/j.jacc.2015.12.005.
- ↑ Allam J.-P., Bunzek C., Schnell L., Heltzel M., Weckbecker L., Wilsmann-Theis D., Brendes K., Haidl G., Novak N. (Aug 2019). "Low serum testosterone levels in male psoriasis patients correlate with disease severity". European journal of dermatology 29 (4): 375-82 doi:10.1684/ejd.2019.3605.
- ↑ Kelly D. M., Jones T. H. (Apr 2013). Testosterone: a metabolic hormone in health and disease. 217. pp. R25-45 doi:10.1530/JOE-12-0455.
- ↑ Panizzon M. S., Hauger R. L., Xian H., Jacobson K., Lyons M. J., Franz C. E., Kremen W. S. (Mai 2018). "Interactive effects of testosterone and cortisol on hippocampal volume and episodic memory in middle-aged men". Psychoneuroendocrinology 91: 115-22 doi:10.1016/j.psyneuen.2018.03.003.
Bibliographia
recensere- "Molecular Biology of Androgen Action: Perspectives on Neuroprotective and Neurotherapeutic Effects.". Molecular Mechanisms of Hormone Actions on Behavior. Elsevier Inc.. 2010. pp. 1219–1246. ISBN 978-0-12-374939-0.
- "Sperm, testosterone, masculinities and fatherhood". Nevada Law Journal 13 (2): 8. 2013.
- "On the effects of testosterone on brain behavioral functions". Frontiers in Neuroscience 9: 12. Februarius 2015.