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Cyclus ex [[pyruvatum|pyruvato]] et, non exigue, [[aqua]] generat duo substantias, electrona ''e<sup>-</sup>'' in proximum iter portantes: [[Nicotinamidum adeninum dinucleotidum|NADH]]+H<sup>+</sup> et FAD(2H).
 
Cyclus hic anno [[1937]] ab [[Hans Adolphus Krebs|Hans Adolphum Krebs]] primo descriptus est; nimirum Krebs anno 1953 [[Praemium Nobelianum physiologiae et medicinae]] addictum est<ref>[http://nobelprize.org/nobel_prizes/medicine/laureates/1953/index.html De Hans Adolpho Krebs] in situ Praemio Nobeliano Medicinae dicato {{Ling|Anglice}}</ref>. Hac de causa cyclus non raro "cyclus Krebs" dicitur. Praeterea, nomen "cycli acidorum triclyclicorum" de tribus acidis tricyclicis intra cyclum Krebs (citratum, isocitratumaconitatum, aconitatumisocitratum) partibus cursus cycli; Denique, nomen "cycli acidi citrici" de [[molecula]] [[acidum citricum|acidi citrici]], non electrice onerati, derivatur, quamquam ''citratum'' forma [[ion|electrice onerata]] partem cycli ipsius capit.
 
== Cursus ==
=== Condiciones ===
* Substrata [[pyruvatum]] generantia
* [[Aqua]] (cyclo 2 moleculae)
* [[Mitochondrium|Mitochondria]] sana
 
=== Gradus cycli acidi citrici ===
* Reactio biochemica 0/10 (Citrati synthasis): Oxaloacetatum + Acetylo-CoA + [[Aqua|H<sub>2</sub>O]] → Citratum + CoA-SH
* Reactio biochemica 1 (Aconitasis): Citratum + CoA-SH → ''cis''-Aconitatum + H<sub>2</sub>O
* Reactio biochemica 2 (Aconitasis): ''cis''-Aconitatum + [[Aqua|H<sub>2</sub>O]] → Isocitratum
* Reactio biochemica 3 (Isocitrati dehydrogenasis): Isocitratum + NAD<sup>+</sup> → Oxalosuccinatum + NADH + H<sup>+</sup>
* Reactio biochemica 4 (Isocitrati dehydrogenasis): Oxalosuccinatum → α-Ketoglutaratum + CO<sub>2</sub>
* Reactio biochemica 5 (α-Ketoglutarate dehydrogenasis): α-Ketoglutaratum + NAD<sup>+</sup> + CoA-SH → Succinylo-CoA + NADH + H<sup>+</sup> + CO<sub>2</sub>
* Reactio biochemica 6 (Succinylo-CoA synthetasis): Succinylo-CoA + [[GDP]] + [[Phosphatum|P<sub>i</sub>]] → Succinatum + CoA-SH + [[GTP]]
* Reactio biochemica 7 (Succinati dehydrogenasis): Succinatum + [[Coenzymum Q10|Ubiquinonum (Q)]] → Fumaratum + Ubiquilonum (QH<sub>2</sub>)
* Reactio biochemica 8 (Fumarasis): Fumaratum + [[Aqua|H<sub>2</sub>O]] → <small>L</small>-Malatum
* Reactio biochemica 9 (Malati dehydrogenasis) <small>L</small>-Malatum + NAD<sup>+</sup> → Oxaloacetatum + NADH + H<sup>+</sup>
* Reactio biochemica 10/0 (Citrati synthasis): Oxaloacetatum + Acetylo-CoA + H<sub>2</sub>O → Citratum + CoA-SH
 
=== Eventus ===
* [[Electron]]a (cyclo 3 moleculae NADH+H<sup>+</sup>, 1 molecula FAD(2H))
* GTP (cyclo 1 molecula)
* CO<sub>2</sub> (cyclo 2 moleculae, aeris exspirati)
 
== Notae ==
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