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[[Fasciculus:Sjogren's syndrome (2).jpg|thumb|Imago [[microscopium|microscopio]] vista sectionis [[glandulae salivariae|glandulae salivarii]] infiltrationem lymphoideam focalem demonstrans. [[Coloratio haematoxylino eosinoque|Coloratione H&E]].]]
'''Syndroma Sjögren''' {{victio|Syndroma Sjögren|ae Sjögren|f}} est [[morbus]] autoimmunologicus chronicus, qui [[glandula]]s substantias liquidas secernentes (glandulas exocrinas) temptat inhibitque earum functiones ''infiltrationibus [[lymphocytus|lymphocyticis]]'' ita, ut ''trias'' symptomatum ''siccitates [[os (anatomia oris)|oris]]'' ([[xerostomia (symptoma)|xerostomia]]) et [[oculus|''oculorum'']] ([[xerophthalmia (symptoma)|xerophthalmia]]), observanturvelut praeclare [[symptoma]]ta signaque [[systema immunitatis|''systematis immunitatis'']] [[inflammatio]] observetur<ref>{{cite journal |authors=Fox R. I., Stern M., Michelson P. |title=Update in Sjögren Syndrome |journal=Current opinion in rheumatology |year=2000 |volume=12 |issue=5 |pages=391-8 |url=https://www.ncbi.nlm.nih.gov/pubmed/10990175}}</ref>. Praeterea aliae corporis partes affectae sunt, ut [[articulus|articuli]], [[tendo|tendines]], [[ligamentum|ligamenta]], [[os (anatomia ossis)|ossa]], [[musculus|musculi]], velut [[cutis]], [[pulmo]]nes, [[ren]]es, [[vas sanguineum|vasa sanguinea]], [[apparatus digestorius|organa digestoria]], [[nervus|nervi]].
Saepe et praeclare [[symptoma]]ta signaque [[inflammatio]]nis observatur: Tumor, dolor, rubor, calor, functio laesa.
 
Incipit syndroma Sjögren imprimis in foeminis plus quam quadraginta annos natis; viri rarius affecti sunt.
== Pathophysiologia ==
Deminutionem functionum [[glandulae salivariae|glandularum salivariarum]] varios effectus perficiunt. In [[glandula lacrimalis|''glandulis lacrimalibus'']], per exemplum, eventus malorum autoimmunologicorum imprimis [[epithelium|structuris epithelialibus]] (epithelitis autoimmunologica chronica) adhaerent<ref>{{cite journal |authors=Pflugfelder S. C., Crouse C. A., Monroy D., Yen M., Rowe M., Atherton S. S. |title=Epstein-Barr virus and the lacrimal gland pathology of Sjögren's syndrome |journal=American journal of pathology |year=1993 |volume=143 |issue=1 |pages=49-64 |url=https://www.ncbi.nlm.nih.gov/pubmed/8391219}}</ref>. Sequitur siccitatem oculorum cum prurito oculorum et signis inflammatoria.
 
== Symptomata et signa ==
''Trias symptomatum'' ex siccitatibus oris (xerostomia) et oculorum (xerophthalmia) velut signis [[systema immunitatis|systematis immunitatis]] effervescentis omnibus syndromati Sjögren atribuuntur. Praeterea aliae corporis partes affectae sunt, ut [[articulus|articuli]], [[tendo|tendines]], [[ligamentum|ligamenta]], [[os (anatomia ossis)|ossa]], [[musculus|musculi]], velut [[cutis]], [[pulmo]]nes, [[ren]]es, [[vas sanguineum|vasa sanguinea]], [[apparatus digestorius|organa digestoria]], [[nervus|nervi]]. Saepe et praeclare symptomata signaque inflammationis actionum ope systematis immunitatis observatur: Tumor, dolor, rubor, calor, functio laesa.
 
== Notae ==
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