Pyruvati kinasis

Pyruvati kinasis est enzymum glycolysis termino, quod gregem phosphati ab phosphoenolpyruvato ad ADP transfert, ita pyruvatum et ATP formans.

Structura trium dimensionum enzymi pyruvati kinasis. In medio moleculae minores phosphoenolpyruvati (rubre) et phosphati depicta

A phosphoenolpyruvato ad pyruvatum Cofactor: Mg2+ Haec reactio consumit energiam. ΔG° = -31,4 kJ/mol.

Phosphoenolpyruvatum Pyruvati kinasis Pyruvatum ADP ATP H+ (Mg2+)

Quattuor isoformae enzymi notae sunt:

• L — in iecore, renibus
• M1 — in musculis, cerebro, leucocytis, thrombocytis
• M2 — solum in textibus foetalibus et tumoribus
• R — in erythrocytis

Nexus interni

• Cancer (morbus)

Nexus externi

• U. S. National Library of Medicine de pyruvati kinasi (Anglice)