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Fasciculus:Proton pump inhibitors structure.svg

Sua resolutio ‎(fasciculus SVG, nominale 512 × 227 elementa imaginalia, magnitudo fasciculi: 10 chiliocteti)

Hic fasciculus apud Vicimedia Communia iacet; in aliis inceptis adhiberi potest. Contenta paginae descriptionis fasciculi subter monstrantur.

Summarium

Descriptio
English: Common structure of proton pump inhibitors. Asterisk indicates stereocenter. Dots indicate lone pair.
Datum
Fons Opus proprium
Auctor Anypodetos
Permissio
(Reusing this file)
Public domain This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship.
Compound Substituents Form Cysteine binding pKa First approval
X R1 R2 R3 R4 pKaa1 pKaa1 year
Omeprazole CH OCH3 CH3 CH3 CH3 Racemic mixture 813 and 892 4.06 0.79 1989 in USA
Esomeprazole CH OCH3 CH3 CH3 CH3 (S)-(−)-enantiomer of lansoprazole 813 and 892 4.06 0.79 2001 in USA
Lansoprazole CH H CH3 CH2CF3 H Racemic mixture 813 and 321 3.83 0.62 1991 in Europe
Dexlansoprazole CH H CH3 CH2CF3 H (R)-(+)-enantiomer of lansoprazole 813 and 321 3.83 0.62 2009 in USA
Pantoprazole CH OCHF2 OCH3 CH3 H Racemic mixture 813 and 822 3.83 0.11 1994 in Germany
Rabeprazole CH H CH3 (CH2)3OCH3 H Racemic mixture 813, 892 and 321 4.53 0.62 1999 in USA
Tenatoprazole N OCH3 CH3 CH3 CH3 Racemic mixture 813 and 822 4.04 –0.12 —
 
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inceptio

7 Februarii 2012

Historia fasciculi

Presso die vel tempore fasciculum videbis, sicut tunc temporis apparuit.

Dies/TempusMinutioDimensionesUsorSententia
recentissima12:11, 7 Decembris 2015Minutum speculum redactionis 12:11, 7 Decembris 2015 factae512 × 227 (10 chiliocteti)Vaccinationistfacelifting
19:05, 8 Februarii 2012Minutum speculum redactionis 19:05, 8 Februarii 2012 factae275 × 135 (35 chiliocteti)AnypodetosMark stereocenter
14:31, 7 Februarii 2012Minutum speculum redactionis 14:31, 7 Februarii 2012 factae275 × 135 (34 chiliocteti)Anypodetos{{Information |Description ={{en|1=Common structure of {{w|proton pump inhibitor}}s}} |Source ={{own}} |Author =Anypodetos |Date =2012-02-07 |Permission = |other_versions = }} {{BKchem}}{{Inkscape}} [[C

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Hic fasciculus alias res continet, saepius a machina originatore additas, et (si fasciculus postea recensus sit) fortasse corrigendas.

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